the second time around

Back in the fall, in biochemistry, we learned about Lesch-Nyhan disease. People with Lesch-Nyhan are deficient in an enzyme called HGPRT involved in purine salvage, which leads to uric acid buildup. I remember these details because the other thing about people with Lesch-Nyhan is that they for some reason also mutilate themselves. They bite their own lips and fingers. Completely helpless to stop themselves, people with this disease often bandage their hands to prevent inflicting hurt upon themselves. Our professor referred us to a New Yorker article about a man with Lesch-Nyhan, and how the lack of control in self-mutilation pervades his entire approach to life. Instead of telling someone he loves them, he swears at them. Seeing a sharp pencil induces an uncontrollable urge to take it and do harm. He uses his right hand to grab and restrain his left hand from grabbing a knife and hurting himself or someone else. His intentions and his actions are completely at odds, and they divide his body.

The author of the article framed the disease as the extreme end of a phenomenon of which we are all victim, what Edgar Allen Poe termed "the imp of the perverse." The idea that we all do things that we know are bad for ourselves, like eating too much junk food to the point it's not pleasurable anymore or contemplating swerving your car into oncoming traffic for no particular reason. I remember first learning about this strange, rare disease and thinking that I must have some emotional form of Lesch-Nyhan, where I perpetuate things that I know, in mind and in heart, are not good for me and will hurt me.

Doing it once made me none the wiser the second time around. In a recent lecture about the biological basis of pain, we learned that when you feel a certain kind of pain for the second time, you feel it more acutely because you know its character. I'm not sure about the implications about your recovery and resilience, because I would guess there is also a desensitization process, the idea that pain makes you stronger and more able the next time. But what was clear is that once you get to know pain through first encounter, you are more aware when it hits you again. You don't have to feel around in the dark to learn its edges and figure out how to hold it. You know its contours without exploration.

The professor who lectured on pain did make a mistake, though, when he alluded to Lesch-Nyhan and said that people with the disease don't feel pain when they self-mutilate. I distinctly remember that they do feel pain, but the awareness of it can't stop them from hurting themselves. For them there is no desensitization or increased strength, only a constant fight against recurring pain. But I admired the man in the article, because there was a deliberate fight, a will against what he did to himself even if he knew it would continue.

For all the mistakes that I make twice and three times, growth does lurk in the corners. Despite similar themes, and a similar trajectory of trying not to hurt anyone and in the process hurting everyone including myself--there are different circumstances, reasons, people, feelings, and most importantly, more things learned. It does make me wonder again if I'll ever feel the same as I did the first time around. That used to worry me, but now I know that each thing offers something else, and it's valuable. And if I experience that feeling again, it will still have newness and surprises and a sense of other. It makes me think that for the man with Lesch-Nyhan, each finger bitten is not quite the same, and that even though you know the shape of its pain, you still reach out to find something different.

When I told Guson I was going home before summer because I missed my parents, he said I was maturing. My immediate reaction was to reject that idea, because isn't growing up about not missing home, not needing your parents? But it turns out he was right. There's only been one other time when I made sudden plans to go home. That time was a result of wanting to be away from where I was, a push from there to home. This time, I don't feel a push away from anything--I absolutely love where I am, in all senses--instead, it's a pull from home. That time I felt a little weak and this time I feel stronger. This time around, it's different.